Delay in Diagnosis and Treatment of Head and Neck cancer patients: A systematic review and Meta-analysis
Keywords:
Head and Neck Cancer (HNC), Primary delay, Secondary delay, Tertiary delayAbstract
Background: There is a high death rate, low quality of life, and increased risk of sickness for individuals with head and neck cancer (HNC) due to diagnostic and treatment delays. People with HNC have limited access to research that aim to estimate the delay.
Objective: Assessment of diagnostic and therapy delays among HNC patients is the focus of this research.
Method: To locate papers published in reputable sources like Medline, Google Scholar, and PubMed that dealt with HNC, a thorough systematic literature search was undertaken. Primarily, secondaryly, and tertiaryly, we have employed delays. The data is shown as Mean ± SD, and when comparing them, the mean difference is used.
Result: In all, eight publications made up this research. Some studies investigated different types of delays; seven looked at primary and secondary delays, three at secondary and tertiary delays, and four at primary and tertiary delays together. Primary delay was statistically higher than Secondary (MD: 118.2, 95% CI: 45.08 – 191.37, p =0.002) and Tertiary (MD: 140.25, 95% CI: 11.37 – 269.14, p= 0.03) while Secondary delay was not statistically different from Tertiary (MD: 6.2, 95% CI: -0.11 – 12.50, p = 0.05).
Conclusion: Time from the beginning of symptoms to the initial consultation was shown to be the longest delay in the present investigation, followed by secondary and tertiary delays. These delays can lead to disease severity and poor quality of life, and it is important to evaluate and reduce it.
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